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Product Name
IL15RA Polyclonal Antibody
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Description
Polyclonal antibody to IL15RA
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Tested applications
WB
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Species reactivity
Human
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Alternative names
IL15RA antibody; CD215 antibody; interleukin-15 receptor subunit alpha antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human IL15RA
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:1000
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Validations
Western blot - IL15RA Polyclonal Antibody
Western blot analysis of extracts of K-562 cells, using IL15RA antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (By similarity). In neutrophils, binds and activates kinase SYK in response to IL15 stimulation. In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner. Expression of different isoforms may alter or interfere with signal transduction.; Isoform 5: Does not bind IL15.; Isoform 6: Does not bind IL15.; Isoform 7: Does not bind IL15.; Isoform 8: Does not bind IL15.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"