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Product Name
IL12A antibody
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Description
IL12A Mouse Monoclonal antibody. Positive WB detected in Recombinant protein.
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
CLMF antibody; CLMF p35 antibody; IL 12 subunit p35 antibody; IL 12A antibody; IL12A antibody; Interleukin 12 subunit alpha antibody; NFSK antibody; NKSF1 antibody; P35 antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of IL12A recombinant protein (Accession Number: NM_000882). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:1000-1:10000
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Validations
Recombinant protein were subjected to SDS PAGE followed by western blot with Catalog No:107379(IL12A Antibody) at dilution of 1:2000
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Background
IL12A is a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"