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Product Name
IL-28A antibody
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Description
IL-28A Mouse Monoclonal antibody. Positive WB detected in ag18525. Positive IHC detected in human tonsillitis tissue, human small intestine tissue. Observed molecular weight by Western-blot: 34 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
Cytokine Zcyto20 antibody; IFN lambda 2 antibody; IFNL2 antibody; IL 28A antibody; IL28A antibody; IL-28A antibody; Interferon lambda 2 antibody; Interleukin 28A antibody; ZCYTO20 antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of IL-28A recombinant protein (Accession Number: NM_172138). Purification method: Protein G purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:5000-1:50000
IHC: 1:20-1:200
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Validations
Recombinant protein were subjected to SDS PAGE followed by western blot with Catalog No:107396(IL28A Antibody) at dilution of 1:5000
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:107396(IL28A Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using Catalog No:107396(IL28A Antibody) at dilution of 1:50 (under 40x lens)
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Background
IL28A, also named as IFNL2 and ZCYT020, is a cytokine with immunomodulatory activity. It up-regulates MHC class I antigen expression. IL28A is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. It plays a significant role in the antiviral immune defense in the intestinal epithelium.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"