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Product Name
IGFBP2 antibody
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Description
IGFBP2 Rabbit Polyclonal antibody. Positive WB detected in MCF7 cells. Positive IP detected in SH-SY5Y cells. Positive IHC detected in human prostate cancer tissue. Observed molecular weight by Western-blot: 36kd
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Tested applications
ELISA, WB, IHC, IP
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Species reactivity
Human, Mouse; other species not tested.
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Alternative names
BP2 antibody; IBP 2 antibody; IBP2 antibody; IGF binding protein 2 antibody; IGF BP53 antibody; IGFBP 2 antibody; IGFBP2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of IGFBP2 recombinant protein (Accession Number: NM_000597). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
IHC: 1:20-1:200
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Validations
MCF7 cells were subjected to SDS PAGE followed by western blot with Catalog No:111685(IGFBP2 antibody) at dilution of 1:300
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:111685(IGFBP2 antibody) at dilution of 1:50 (under 10x lens)
IP Result of anti-IGFBP2 (IP:Catalog No:111685, 4ug; Detection:Catalog No:111685 1:300) with SH-SY5Y cells lysate 1200ug.
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Background
Insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) have important metabolic roles in the human body. IGFBP-2 is a 34 kD IGFBP protein with degraded fragments of 24 kD, 19kd and 15kd. The levels of IGFBP2 are elevated during progression of many human cancers.
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References
- Kim H, Xu H, Yao Q. Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism. Nature communications. 5:5482. 2014.
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