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Product Name
IGF1B-Specific antibody
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Description
IGF1B-Specific Rabbit Polyclonal antibody. Positive IHC detected in human liver cancer. Positive WB detected in PC-3 cells, human brain tissue. Observed molecular weight by Western-blot: 26kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
human, mouse, rat; other species not tested.
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Alternative names
IGF1 antibody; Insulin like growth factor I antibody; IGF1B antibody; IBP1 antibody; MGF antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_001111285). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:111677(IGF1B-Specific antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human liver cancer using Catalog No:111677(IGF1B-Specific antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human liver cancer using Catalog No:111677(IGF1B-Specific antibody) at dilution of 1:50 (under 40x lens)
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Background
IGF1B, also named as IBP1, MGF, IGF-I and Somatomedin-C, belongs to the insulin family. IGF1 is structurally and functionally related to insulin but have a much higher growth-promoting activity. Altered expression or mutation of IGF-1 is associated with several human disorders, including type I diabetes and various forms of cancer. Defects in IGF1 are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness and mental retardation. The antibody is specific to isoform IGF-1B.
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