Product Name

Icam1 antibody

Documents

Description

Icam1 Rabbit Polyclonal antibody. Positive IHC detected in mouse liver tissue. Positive WB detected in mouse brain tissue. Observed molecular weight by Western-blot: 85-95 kDa

Tested applications

ELISA, WB, IHC

Species reactivity

Mouse,Rat; other species not tested.

Alternative names

CD54 antibody; ICAM 1 antibody; Icam1 antibody; Ly 47 antibody; MALA 2 antibody

Isotype

Rabbit IgG

Preparation

This antibody was obtained by immunization of Recombinant Protein (Accession Number: NM_010493). Purification method: Antigen affinity purified.

Clonality

Polyclonal

Formulation

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Storage instructions

Store at -20℃. DO NOT ALIQUOT

Applications

Recommended Dilution:

WB: 1:1000-1:10000

IHC: 1:20-1:200

Validations

mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:111586(Icam1 antibody) at dilution of 1:4000

Immunohistochemistry of paraffin-embedded mouse liver tissue slide using Catalog No:111586(Icam1 Antibody) at dilution of 1:200 (under 10x lens)

Immunohistochemistry of paraffin-embedded mouse liver tissue slide using Catalog No:111586(Icam1 Antibody) at dilution of 1:200 (under 40x lens)

Background

ICAM-1 (Intercellular Adhesion Molecule-1, CD54) is a glycosylated, transmembrane protein, a member of Ig super family. This protein involves in cell adhesion by interacting with a number of 2 integrin family members such as LFA-1 and Mac-1. Its expression is regulated by chemokines. This protein migrates approximately 115 kDa on SDS gels.

References

Roland CL, Dineen SP, Toombs JE. Tumor-derived intercellular adhesion molecule-1 mediates tumor-associated leukocyte infiltration in orthotopic pancreatic xenografts. Experimental biology and medicine (Maywood, N.J.). 235(2):263-70. 2010.
Suzuki AM, Yoshimura A, Ozaki Y, Kaneko T, Hara Y. Cyclosporin A and phenytoin modulate inflammatory responses. Journal of dental research. 88(12):1131-6. 2009.
Arakawa Y, Shimada M, Utsunomiya T, Imura S, Morine Y, Ikemoto T. Effects of pegylated interferon α2b on metastasis of hepatocellular carcinoma. The Journal of surgical research. 172(1):95-101. 2012.
Zhu H, Shao Q, Sun X. Bone marrow cells: Important role on neovascularization of hepatocellular carcinoma. Journal of gastroenterology and hepatology. 27(7):1241-51. 2012.
Sun XT, Yuan XW, Zhu HT. Endothelial precursor cells promote angiogenesis in hepatocellular carcinoma. World journal of gastroenterology. 18(35):4925-33. 2012.
Garin A, Meyer-Hermann M, Contie M. Toll-like receptor 4 signaling by follicular dendritic cells is pivotal for germinal center onset and affinity maturation. Immunity. 33(1):84-95. 2010.
Chen G, Zhao J, Yin Y. C-type natriuretic peptide attenuates LPS-induced endothelial activation: involvement of p38, Akt, and NF-κB pathways. Amino acids. 46(12):2653-63. 2014.
Wang YS, Li YX, Zhao P. Anti-inflammation Effects of Oxysophoridine on Cerebral Ischemia-Reperfusion Injury in Mice. Inflammation. 38(6):2259-68. 2015.

Icam1 antibody

Product Information

Related Products / Services