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Product Name
humanin antibody
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Description
humanin Rabbit Polyclonal antibody. Positive IHC detected in human small intestine tissue, human colon tissue, human heart tissue.
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Tested applications
ELISA, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
humanin antibody; l rRNA antibody; MTRNR2 antibody; RNR2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NC_012920). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
IHC: 1:20-1:200
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Validations
Immunohistochemistry of paraffin-embedded human heart tissue slide using Catalog No:111723(humanin Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human heart tissue slide using Catalog No:111723(humanin Antibody) at dilution of 1:50 (under 40x lens)
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using Catalog No:111723(humanin Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human small intestine tissue slide using Catalog No:111723(humanin Antibody) at dilution of 1:50 (under 40x lens)
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Background
Humanin, also named as MT-RNR2, is a mitochondrial peptide. It plays a role as a neuroprotective factor. It protects against death induced by multiple different familial Alzheimer disease genes and beta amyloid proteins in Alzheimer disease. Humanin reduces the aggregation and fibrillary formation by suppressing the effect of APP on mononuclear phagocytes and acts by competitively inhibiting the access of FPRL1 to APP.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"