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Product Name
Human VSTM1/UNQ3033/PRO9835 (His tag) recombinant protein
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Description
V-set and transmembrane domain-containing protein 1 is a single-pass membrane protein. VSTM1 Contains 1 Ig-like V-type domain, in humans is encoded by the VSTM1 gene. It expressed on myeloid (neutrophils, eosinophils and monocytes) but not on lymphoid cells. It behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17). Inhibitory immune receptor involved in the regulation of phagocytes.
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Protein name
V-set and transmembrane domain containing 1(VSTM1)
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Protein short names
UNQ3033; PRO9835
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Uniprot ID
Q6UX27
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human VSTM1/UNQ3033/PRO9835 Tyr17-Thr135 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human VSTM1/UNQ3033/PRO9835 (His tag) recombinant protein
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