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Product Name
Human VANGL2 Recombinant protein (His tag)
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Description
Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity). {UniProtKB:Q91ZD4}.
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Protein name
Vang-like protein 2
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Protein short names
KIAA1215; STB1
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Uniprot ID
Q9ULK5
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Gene Name
VANGL2; KIAA1215; STB1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
268-322 aa encoded by BC103920 was inserted into PET28a vector
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human VANGL2 SDS-PAGE
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