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Product Name
Human UBE2S/E2EPF/OK/SW-cl.73 (GST tag) recombinant protein
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Description
Ubiquitin-Conjugating Enzyme E2 S (UBE2S) is a member of the Ubiquitin-Conjugating Enzyme family. UBE2S interacts with CDC20, FZR1/CDH1 and VHL. UBE2S can form a thiol ester linkage with Ubiquitin in an Ubiquitin Activating Enzyme-Dependent manner, a characteristic property of Ubiquitin Carrier Proteins. UBE2S acts as an essential factor of the Anaphase Promoting Complex/Cyclosome, a cell cycle-regulated Ubiquitin ligase that controls progression through mitosis. UBE2S is also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A.
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Protein name
ubiquitin conjugating enzyme E2 S(UBE2S)
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Protein short names
E2EPF; OK; SW-cl.73
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Uniprot ID
Q16763
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human UBE2S/E2EPF/OK/SW-cl.73 Met1-Leu222 is expressed with a GST tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human UBE2S/E2EPF/OK/SW-cl.73 (GST tag) recombinant protein
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