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Product Name
Human TYW1B Recombinant protein (GST tag)
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Description
Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity).
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Protein name
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase
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Protein short names
RSAFD2
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Uniprot ID
Q6NUM6
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Gene Name
TYW1B; RSAFD2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human TYW1B (NP_001138912.2) 319-668 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human TYW1B SDS-PAGE
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