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Product Name
Human TRPC4AP Recombinant protein (His tag)
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Description
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1. {PubMed:20551172}.
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Protein name
Short transient receptor potential channel 4-associated protein
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Protein short names
C20orf188; TRRP4AP
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Uniprot ID
B2RDK8
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Gene Name
TRPC4AP; C20orf188; TRRP4AP
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human TRPC4AP (XP_047296051.1) 22-350 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human TRPC4AP SDS-PAGE
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