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Product Name
Human TRIM5/RNF88 (His tag) recombinant protein
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Description
Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC family.It contains 1 B box-type zinc finger, 1 B30.2/SPRY domain and 1 RING-type zinc finger. TRIM5 present in the cytoplasm recognizes motifs within the capsid proteins and interferes with the uncoating process, therefore preventing successful reverse transcription and transport to the nucleus of the viral genome. The exact mechanism of action has not been shown conclusively, but capsid protein from restricted viruses is removed by proteasome-dependent degradation
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Protein name
tripartite motif containing 5(TRIM5)
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Protein short names
RNF88
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Uniprot ID
Q9C035
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human TRIM5/RNF88 Met1-Gln248 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human TRIM5/RNF88 (His tag) recombinant protein
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