Human TRIM5/RNF88 (His tag) recombinant protein

Cat.#: 518527

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Product Information

  • Product Name
    Human TRIM5/RNF88 (His tag) recombinant protein
  • Documents
  • Description
    Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC family.It contains 1 B box-type zinc finger, 1 B30.2/SPRY domain and 1 RING-type zinc finger. TRIM5 present in the cytoplasm recognizes motifs within the capsid proteins and interferes with the uncoating process, therefore preventing successful reverse transcription and transport to the nucleus of the viral genome. The exact mechanism of action has not been shown conclusively, but capsid protein from restricted viruses is removed by proteasome-dependent degradation
  • Protein name
    tripartite motif containing 5(TRIM5)
  • Protein short names
    RNF88
  • Uniprot ID
    Q9C035
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human TRIM5/RNF88 Met1-Gln248 is expressed with a 6His tag at the N-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human TRIM5/RNF88 (His tag) recombinant protein

    Human TRIM5/RNF88 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"