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Product Name
Human TPP1/CLN2/GIG1/UNQ267/PRO304 (His tag) recombinant protein
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Description
Tripeptidyl-Peptidase 1 (TPP1) belongs to the peptidase S53 family. TPP1 is detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues. TPP1 is lysosomal serine protease with tripeptidyl-peptidase I activity. TPP1 may act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. TPP1 requires substrates with an unsubstituted N-terminus. TPP1 mutations have also been shown to cause neuronal ceroid lipofuscinosis type 2 (CLN2).
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Protein name
tripeptidyl peptidase 1(TPP1)
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Protein short names
CLN2; GIG1; UNQ267; PRO304
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Uniprot ID
O14773
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human TPP1/CLN2/GIG1/UNQ267/PRO304 Ser20-Pro563 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human TPP1/CLN2/GIG1/UNQ267/PRO304 (His tag) recombinant protein
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