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Product Name
Human TNFRSF25/APO3/DDR3 (Fc tag) recombinant protein
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Description
Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) contains 1 death domain and 4 TNFR-Cys repeats. TNFRSF25 is a cell surface receptor of the tumor necrosis factor receptor superfamily which mediates apoptotic signalling and differentiation, activated by a monogamous ligand, known as TL1A (TNFSF15), which is rapidly upregulated in antigen presenting cells and some endothelial cells following Toll-Like Receptor or Fc receptor activation. This receptor has been shown to signal both through the TRADD adaptor molecule to stimulate NF-kappa B activity or through the FADD adaptor molecule to stimulate caspase activation and regulate cell apoptosis. It may play a role in regulating lymphocyte homeostasis.
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Protein name
TNF receptor superfamily member 25(TNFRSF25)
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Protein short names
APO3; DDR3; DR3; TNFRSF12; WSL; WSL1; UNQ455; PRO779
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Uniprot ID
Q93038
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human TNFRSF25/APO3/DDR3 Gln25-Phe201 is expressed with a Fc tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human TNFRSF25/APO3/DDR3 (Fc tag) recombinant protein
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