Human TMED1 (His Tag) recombinant protein

Human TMED1 (His Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

TMED1 belongs to the EMP24/GP25L family. It contains 1 GOLD domain and is widely expressed. TMED1 binds to its receptor IL1RL1 and results in the activation of DNA binding by nuclear factor NF-kappa-B or transcription from the IL8 promoter and most likely requires other proteins to elicit these activities. Dendritic cells from Peyer's patches (but not from spleen) express TMED1 in response to treatment with LPS. TMED1 may play a role in vesicular protein trafficking, mainly in the early secretory pathway. It may act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side.

Transmembrane emp24 domain-containing protein 1

IL1RL1-BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR-LIKE 1 LIGAND; TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 1; P24 FAMILY PROTEIN GAMMA-1; PUTATIVE T1/ST2 RECEPTOR-BINDING PROTEIN; T1/ST2 RECEPTOR BINDING PROTEIN; IL1RL1LG; ST2L; TP24; P24GAMMA1; LY84L; TRANSMEMBRANE EMP24 DOMAIN CONTAINING 1; LYMPHOCYTE ANTIGEN 84 LIGAND; IL1RL1L

Q13445

TMED1; IL1RL1L; IL1RL1LG

Human Cells

A DNA sequence encoding the human TMED1 (Q13445) (Met1-Asn194) was expressed with a polyhistidine tag at the C-terminus.

Human

The recombinant human TMED1 consists of 182 amino acids and predicts a molecular mass of 20.6 KDa. It migrates as an approximately 28 KDa band in SDS-PAGE under reducing conditions.

> 90 % as determined by SDS-PAGE