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Product Name
Human TLR9 Recombinant protein (His tag)
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Description
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection. {PubMed:11564765, PubMed:17932028}.
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Protein name
Toll-like receptor 9
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Uniprot ID
H0Y858
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Gene Name
TLR9; UNQ5798/PRO19605
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human TLR9 (NP_059138.1) 32-353 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human TLR9 SDS-PAGE
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