Human TIMM13 Recombinant protein (GST tag)

Human TIMM13 Recombinant protein (GST tag)

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Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. {PubMed:11489896, PubMed:15254020}.

Mitochondrial import inner membrane translocase subunit Tim13

TIM13B; TIMM13A; TIMM13B

Q9Y5L4

TIMM13; TIM13B; TIMM13A; TIMM13B

E. coli

A DNA sequence encoding the human TIMM13 (NP_036590.1) 1-95 aa was fused with the N-terminal GST tag

Human

Not tested.