Human TGFA recombinant protein

Human TGFA recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Transforming Growth Factor α (TGF-α) belongs to the EGF family of cytokines. It is a mitogenic polypeptide and secreted protein, which is expressed by monocytes, keratinocytes, and various tumor cells. TGFα contains two chains, protransforming growth factor α and transforming growth factor α. It can bind to the EGF receptor that synergistically with TGFβ to stimulate anchorage-independent cell proliferation and produce a mitogenic response. TGFα interacts with the PDZ domains of MAGI3, SDCBP and SNTA1. The interaction with SDCBP is required for the targeting to the cell surface.

transforming growth factor alpha(TGFA)

P01135

E.coli

A DNA sequence encoding the Human TGFA Val41-Val90 is expressed.

Human

>95% as determined by SDS-PAGE.