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Product Name
Human STEAP3 Recombinant protein (His tag)
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Description
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NADP(+) as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP. {PubMed:15319436, PubMed:16651434}.
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Protein name
Metalloreductase STEAP3
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Protein short names
TSAP6
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Uniprot ID
Q658P3
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Gene Name
STEAP3; TSAP6
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human STEAP3 (XP_047300851.1) 11-214 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human STEAP3 SDS-PAGE
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