Human STAM2 Recombinant protein (GST tag)

Human STAM2 Recombinant protein (GST tag)

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Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).

Signal transducing adapter molecule 2

HBP

O75886

STAM2; HBP

E. coli

A DNA sequence encoding the human STAM2 (NP_005834.4) 1-307 aa was fused with the N-terminal GST tag

Human

Not tested.