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Product Name
Human ST6GAL1/SIAT1 (His tag) recombinant protein
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Description
The ST6GAL1 gene encodes β-Galactosamide α-2,6-Sialyltransferase 1. It is a type II membrane protein and is localized to the trans-Golgi network. It catalyzes 2,6-sialylation of Galβ1,4-GlcNAc structures on N-glycans. ST6GAL1 is highly expressed in the liver and other tissues. ST6GAL1 deficiency causes abnormalities in B-cell immunoreactivity. The expression and activity of ST6GAL1 are associated with tumor metastasis in breast and colon cancers. The majority of ST6GAL1 in the liver is cleaved and secreted into the serum and may be used as a biomarker for hepatitis diseases.
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Protein name
ST6 beta-galactoside alpha-2,6-sialyltransferase 1(ST6GAL1)
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Protein short names
SIAT1
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Uniprot ID
P15907
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human ST6GAL1/SIAT1 Lys27-Cys406 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human ST6GAL1/SIAT1 (His tag) recombinant protein
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