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Product Name
Human Sorcin (His & GST Tag) recombinant protein
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Description
Sorcin was originally identified in multidrug-resistant cells. It is a alcium-binding protein. Sorcin modulates excitation-contraction coupling in the heart, contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Sorcin is overexpressed in the multi-drug resistant chinese hamster ovary cell line CHRC5 and a variety of multidrug-resistant tumor cell lines, but overexpression is not a sufficient or necessary condition for the acquisition of the multidrug-resistant phenotype.
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Protein name
Sorcin
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Protein short names
SOR; 22 KDA PROTEIN; SRI; CP22; CP-22; SORCIN; V19; 2210417O06RIK; 2900070H08RIK; SCN; H_RG167B05.1; CALCIUM BINDING PROTEIN AMPLIFIED IN MUTLIDRUG-RESISTANT CELLS
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Uniprot ID
P30626
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Gene Name
SRI
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human SRI (P30626) (Met1-Val198) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human SRI /GST chimera consists of 435 amino acids and has a calculated molecular mass of 49.5 kDa. The recombinant protein migrates as an approximately 47 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human SRI / Sorcin Protein (His & GST Tag) SDS-PAGE
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