Human SIT1/SIT (His tag) recombinant protein

Cat.#: 518814

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Product Information

  • Product Name
    Human SIT1/SIT (His tag) recombinant protein
  • Documents
  • Description
    Signaling Threshold-Regulating Transmembrane Adapter 1 (SIT1) is a single-pass type I membrane protein and specifically expressed in T- and B-cells. SIT1 interacts with PTPN11/SHP2, GRB2 and CSK, when it is phosphorylated. SIT1 negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cell. In addition, SIT1 is involved in positive selection of T-cells.
  • Protein name
    signaling threshold regulating transmembrane adaptor 1(SIT1)
  • Protein short names
    SIT
  • Uniprot ID
    Q9Y3P8
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human SIT1/SIT Gln65-Ser196 is expressed with a 6His tag at the N-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human SIT1/SIT (His tag) recombinant protein

    Human SIT1/SIT (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"