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Product Name
Human SH3KBP1/CIN85 (His tag) recombinant protein
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Description
SH3 Domain-Containing Kinase-Binding Protein 1 (SH3KBP1) contains 3 SH3 domains. SH3KBP1 is widely expressed in many tissues, it is also expressed in some cancer cell lines. SH3KBP1 plays a role in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases. SH3KBP1 is involved in regulation of ligand-dependent endocytosis of the IgE receptor and in the regulation of cellular stress response via the MAPK pathways. SH3KBP1 is also required for the control of cell shape and migration.
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Protein name
SH3 domain containing kinase binding protein 1(SH3KBP1)
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Protein short names
CIN85
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Uniprot ID
Q96B97
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human SH3KBP1/CIN85 Met1-Lys665 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human SH3KBP1/CIN85 (His tag) recombinant protein
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