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Product Name
Human SGTA/SGT/SGT1 (His tag) recombinant protein
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Description
Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein α (SGTA) is an ubiquitously expressed protein which belongs to the SGT Family. SGTA contains three TPR Protein-Protein Interaction Duplicates. SGTA is a co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. SGTA is capable of interacting with the major nonstructural protein of Parvovirus H-1 and 70-kDa heat shock cognate protein. It interacts with NS1 from Parvovirus H-1, with Vpu and Gag from HIV-1. It also interacts with SARS-CoV Accessory Protein 7a, DNAJC5 and DNAJC5B. However, its function is not known. Since this transcript is expressed ubiquitously in various tissues, SGTA may serve a housekeeping function.
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Protein name
small glutamine rich tetratricopeptide repeat containing alpha(SGTA)
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Protein short names
SGT; SGT1
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Uniprot ID
O43765
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human SGTA/SGT/SGT1 Met1-Glu313 is expressed with a 6His tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human SGTA/SGT/SGT1 (His tag) recombinant protein
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