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Product Name
Human SF3A3 Recombinant protein (GST tag)
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Description
Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.
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Protein name
Splicing factor 3A subunit 3
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Protein short names
SAP61
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Uniprot ID
Q12874
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Gene Name
SF3A3; SAP61
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human SF3A3 (NP_006793.1) 202-501 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human SF3A3 SDS-PAGE
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