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Product Name
Human SEPX1 Recombinant protein (GST tag)
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Description
Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages (By similarity).
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Protein name
Methionine-R-sulfoxide reductase B1
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Protein short names
SEPX1
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Uniprot ID
Q9NZV6
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Gene Name
MSRB1; SEPX1; HSPC270
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human MSRB1 (NP_057416.1) 1-115 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human SEPX1(Full length) SDS-PAGE
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