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Product Name
Human SCIN Recombinant protein (GST tag)
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Description
Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes (By similarity).
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Protein name
Adseverin
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Protein short names
KIAA1905
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Uniprot ID
Q9Y6U3
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Gene Name
SCIN; KIAA1905
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human SCIN (NP_001106177.1) 1-357 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human SCIN SDS-PAGE
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