Human S100A6 (His Tag) recombinant protein

Human S100A6 (His Tag) recombinant protein

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S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. S100A6 (S100 calcium binding protein A6) is a member of the S100 family of proteins, and functions in prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of S100A6 have been implicated in melanoma.

Protein S100-A6

CALCYCLIN; 2A9; CACY; S100A6; 5B10; PRA; CABP

P06703

S100A6; CACY

Baculovirus-Insect Cells

A DNA sequence encoding the human S100A6 (NP_055439.1) (Met 1-Gly 90) was expressed, with a C-terminal polyhistidine tag.

Human

The recombinant human S100A6 consisting of 101 amino acids and migrates as an approximately 12 kDa band in SDS-PAGE under reducing conditions as predicted.

> 96 % as determined by SDS-PAGE