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Product Name
Human RTN4/KIAA0886/NOGO/My043/SP1507 (GST tag) recombinant protein
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Description
RTN4 belongs to multiple-pass membrane peotein, which anchored to the membrane of the endoplasmic reticulum through 2 putative transmembrane domains. It acts as a developmental neurite growth regulatory factor with a roles as a negative regulator of axon-axon adhesion and growth. RTN4 regulates neurite fasciculation, branching and extension in the developing nervous system. It involved in down-regulation of growth, stabilization of wring and restriction of plasticity in the adult CNS. It regulates the radial migration of cortical neurons via an RTN4R-Lingo1 containing receptor complex.
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Protein name
reticulon 4(RTN4)
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Protein short names
KIAA0886; NOGO; My043; SP1507
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Uniprot ID
Q9NQC3-3
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human RTN4/KIAA0886/NOGO/My043/SP1507 Met1-Val185 is expressed with a GST tag at the N-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human RTN4/KIAA0886/NOGO/My043/SP1507 (GST tag) recombinant protein
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