Human RIDA/HRSP12 (His tag) recombinant protein

Cat.#: 519937

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Product Information

  • Product Name
    Human RIDA/HRSP12 (His tag) recombinant protein
  • Documents
  • Description
    Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma.
  • Protein name
    reactive intermediate imine deaminase A homolog(RIDA)
  • Protein short names
    HRSP12
  • Uniprot ID
    P52758
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human RIDA/HRSP12 Met1-Leu137 is expressed with a 6His tag at the N-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human RIDA/HRSP12 (His tag) recombinant protein

    Human RIDA/HRSP12 (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"