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Product Name
Human RGS7 Recombinant protein (His tag)
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Description
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:10521509, PubMed:10862767). The RGS7/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509). May play a role in synaptic vesicle exocytosis (PubMed:12659861). Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling (PubMed:15897264). {PubMed:10521509, PubMed:10862767, PubMed:15897264, PubMed:12659861}.
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Protein name
Regulator of G-protein signaling 7
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Uniprot ID
P49802
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Gene Name
RGS7
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human RGS7 (NP_002915.3) 139-487 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human RGS7 SDS-PAGE
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