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Product Name
Human RASSF7 Recombinant protein (GST tag)
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Description
Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization. {PubMed:20629633, PubMed:21278800}.
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Protein name
Ras association domain-containing protein 7
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Protein short names
C11orf13; HRC1
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Uniprot ID
Q02833
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Gene Name
RASSF7; C11orf13; HRC1
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human RASSF7 (NP_003466.1) 91-292 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human RASSF7 SDS-PAGE
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