Human RASIP1 Recombinant protein (His tag)

Human RASIP1 Recombinant protein (His tag)

• DataSheet
• Material Safety Data Sheets (MSDS)

Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells (By similarity). May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy. {, PubMed:15031288, PubMed:22354037}.

Ras-interacting protein 1

Q5U651

RASIP1

E. coli

A DNA sequence encoding the human RASIP1 (NP_060275.2) 617-963 aa was fused with the polyhistidine tag

Human

Not tested.