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Product Name
Human RANBP9 Recombinant protein (GST tag)
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Description
May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA (By similarity). {, PubMed:12147692, PubMed:12361945, PubMed:14500717, PubMed:14722085, PubMed:15381419, PubMed:15558019, PubMed:18222118}.
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Protein name
Ran-binding protein 9
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Protein short names
RANBPM
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Uniprot ID
Q96S59
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Gene Name
RANBP9; RANBPM
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human RANBP9 (NP_005484.2) 498-715 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human RANBP9 SDS-PAGE
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