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Product Name
Human PYM1/PYM/WIBG (His tag) recombinant protein
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Description
Partner of Y14 and Mago (WIBG) is a key regulator of the Exon Junction Complex (EJC). EJC is a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs, is a positional landmarker for the intron exon structure of genes, and directs post-transcriptional processes in the cytoplasm, for instance mRNA export, nonsense-mediated mRNA decay or translation. WIBG is a cytoplasmic RNA-binding protein, it can be excluded from nucleus by Crm1. WIBG as a cooperateing partner of Mago-14, relates with Mago-14 by its N-terminal domain.
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Protein name
PYM homolog 1, exon junction complex associated factor(PYM1)
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Protein short names
PYM; WIBG
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Uniprot ID
Q9BRP8
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Source/Expression Host
E.coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human PYM1/PYM/WIBG Met1-Leu204 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human PYM1/PYM/WIBG (His tag) recombinant protein
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