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Product Name
Human PTPN11 Recombinant protein (His tag)
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Description
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity. {PubMed:10655584, PubMed:18559669, PubMed:18829466}.
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Protein name
Tyrosine-protein phosphatase non-receptor type 11
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Protein short names
PTP2C; SHPTP2
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Uniprot ID
Q06124
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Gene Name
PTPN11; PTP2C; SHPTP2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human PTPN11 (NP_001317366.1) 1-357 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human PTPN11 SDS-PAGE
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