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Product Name
Human PSENEN Recombinant protein (GST tag)
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Description
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity. {PubMed:12522139, PubMed:12763021}.
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Protein name
Gamma-secretase subunit PEN-2
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Protein short names
PEN2
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Uniprot ID
Q9NZ42
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Gene Name
PSENEN; PEN2; MDS033
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human PSENEN (NP_001268461.1) 1-101 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human PSENEN(Full length) SDS-PAGE
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