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Product Name
Human POMGNT1/MGAT1.2/UNQ746/PRO1475 (His tag) recombinant protein
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Description
Protein O-Linked-Mannose β-1 2-N-Acetylglucosaminyltransferase 1 (POMGNT1) belongs to the Glycosyltransferase 13 family. Amino acid residues between 299-311 are important for both protein expression and enzymatic activity. The minimal catalytic domain is located between positions 299-651. It is suggested that the stem domain of the soluble form is unnecessary for activity, but that some amino acids play a crucial role in the membrane-bound form. Defects in POMGNT1 are the cause of muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies type A3 (MDDGA3).
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Protein name
protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)(POMGNT1)
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Protein short names
MGAT1.2; UNQ746; PRO1475
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Uniprot ID
Q8WZA1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human POMGNT1/MGAT1.2/UNQ746/PRO1475 Leu59-Thr660 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human POMGNT1/MGAT1.2/UNQ746/PRO1475 (His tag) recombinant protein
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