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Product Name
Human PI3/WAP3/WFDC14 (His tag) recombinant protein
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Description
Elafin is a secreted protein. Elafin consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain serves as an anchor to localize Elafin covalently to specific sites on extracellular matrix proteins. It is shown that Elafin can be used as a biomarker for graft versus host disease of the skin. Elafin is expressed in the skin during wound healing through activation of the epidermal growth factor receptor. Elafin may prevent elastase-mediated tissue proteolysis.
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Protein name
peptidase inhibitor 3(PI3)
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Protein short names
WAP3; WFDC14
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Uniprot ID
P19957
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Human PI3/WAP3/WFDC14 Ala23-Gln117 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human PI3/WAP3/WFDC14 (His tag) recombinant protein
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