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  • Human PF4/CXCL4/SCYB4 recombinant protein

Human PF4/CXCL4/SCYB4 recombinant protein

Cat.#: 518893

Special Price 122.3 USD

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Product Information

  • Product Name
    Human PF4/CXCL4/SCYB4 recombinant protein
  • Documents
  • Description
    Human Chemokine (C-X-C motif) Ligand 4 (CXCL4) is expressed in megakaryocytes and stored in the alpha-granules of platelets. CXCL4 contains several heparin-binding sites at the C-terminal region and binds heparin with high affinity. The active CXCL4 protein is a tetramer. Human and mouse CXCL4 share 64% sequence identity. CXCL4 is chemotactic for neutrophils, fibroblasts and monocytes and plays a critical role in inflammation and wound repair. CXCL4 functions via a splice variant of the chemokine receptor CXCR3, known as CXCR3B. The major physiologic role of CXCL4 appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. In contrast to other CXC chemokines, CXCL4 lacks chemotactic activity for polymorphonuclear granulocytes.
  • Protein name
    platelet factor 4(PF4)
  • Protein short names
    CXCL4; SCYB4
  • Uniprot ID
    P02776
  • Source/Expression Host
    E.coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human PF4/CXCL4/SCYB4 Glu32-Ser101 is expressed.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human PF4/CXCL4/SCYB4 recombinant protein

    Human PF4/CXCL4/SCYB4 recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"