Human PCBD1/DCOH/PCBD (His tag) recombinant protein

Cat.#: 518504

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Product Information

  • Product Name
    Human PCBD1/DCOH/PCBD (His tag) recombinant protein
  • Documents
  • Description
    Pterin-4-α-Carbinolamine Dehydratase (PCBD1) is the founding member of the Pterin-4-α-Carbinolamine Dehydratase Family. PCBD1 is involved in Tetrahydrobiopterin biosynthesis. It seems to prevent the formation of 7-Pterins and accelerate the formation of Quinonoid-BH2. Furthermore, PCBD1 regulates the homodimerization of the transcription factor Hepatocyte Nuclear Factor 1 (HNF1) and enhances its transcriptional activity. Defects in PCBD1 are the cause of BH4-Deficient Hyperphenylalaninemia Type D (HPABH4D). HPABH4D is characterized by the excretion of 7-substituted Pterins in the urine of affected patients.
  • Protein name
    pterin-4 alpha-carbinolamine dehydratase 1(PCBD1)
  • Protein short names
    DCOH; PCBD
  • Uniprot ID
    P61457
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Human PCBD1/DCOH/PCBD Ala2-Thr104 is expressed with a 6His tag at the N-terminus.
  • Protein Species
    Human
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    Human PCBD1/DCOH/PCBD (His tag) recombinant protein

    Human PCBD1/DCOH/PCBD (His tag) recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"