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Product Name
Human OTX2 (His tag) recombinant protein
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Description
Homeobox Protein OTX2 is a number of the paired homeobox family of the Bicoid subfamily. OTX2 contains 1 homeobox DNA-binding domain and expresses in brain. OTX2 may play a role in the development of the brain and the sense organs. OTX2 positively regulate of gastrulation and embryonic development. Defects in OTX2 are the cause of microphthalmia syndromic type 5, which is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. It also causes pituitary hormone deficiency combined type 6. Combined pituitary hormone deficiency is defined as the impaired production of growth hormone and one or more of the other five anterior pituitary hormones.
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Protein name
orthodenticle homeobox 2(OTX2)
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Uniprot ID
P32243
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the Human OTX2 Met1-Leu297 is expressed with a 6His tag at the C-terminus.
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Protein Species
Human
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Purity
>95% as determined by SDS-PAGE.
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Validations
Human OTX2 (His tag) recombinant protein
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