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Product Name
Human NUAK2 Recombinant protein (His tag)
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Description
Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1. {PubMed:14575707, PubMed:14976552, PubMed:15345718, PubMed:19927127}.
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Protein name
NUAK family SNF1-like kinase 2
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Protein short names
OMPHK2; SNARK
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Uniprot ID
B4E0Y5
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Gene Name
NUAK2; OMPHK2; SNARK
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human NUAK2 (NP_112214.3) 1-303 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human NUAK2 SDS-PAGE
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