-
Product Name
Human NME1/NDPKA/NM23 (His tag) recombinant protein
- Documents
-
Description
Nucleoside-Diphosphate Kinases (NDKs) are enzymes that catalyze the exchange of phosphate groups between different nucleoside diphosphates. NDKs Possesse nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3-5 exonuclease activities. NDKs involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression and required for neural development including neural patterning and cell fate determination. Prokaryotic NDK forms a functional homotetramer.There are two isoforms of NDK in humans: NDK-A and NDK-B. Both have very similar structure, and can combine in any proportion to form functional NDK hexamers.
-
Protein name
NME/NM23 nucleoside diphosphate kinase 1(NME1)
-
Protein short names
NDPKA; NM23
-
Uniprot ID
P15531
-
Source/Expression Host
E. coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the Human NME1/NDPKA/NM23 Met1-Glu152 is expressed with a 6His tag at the N-terminus.
-
Protein Species
Human
-
Purity
>95% as determined by SDS-PAGE.
-
Validations
Human NME1/NDPKA/NM23 (His tag) recombinant protein
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"