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Product Name
Human NKX3-1 Recombinant protein (His tag)
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Description
Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells. {PubMed:19462257}.
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Protein name
Homeobox protein Nkx-3.1
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Protein short names
NKX3.1; NKX3A
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Uniprot ID
Q99801
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Gene Name
NKX3-1; NKX3.1; NKX3A
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human NKX3-1 (NP_006158.2) 1-234 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human NKX3-1(Full length) SDS-PAGE
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