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Product Name
Human NKX2-2 Recombinant protein (His tag)
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Description
Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity).
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Protein name
Homeobox protein Nkx-2.2
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Protein short names
NKX2.2; NKX2B
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Uniprot ID
O95096
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Gene Name
NKX2-2; NKX2.2; NKX2B
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human NKX2-2 (XP_047296108.1) 1-129 aa was fused with the polyhistidine tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human NKX2-2 SDS-PAGE
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