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Product Name
Human NESP55,GNAS Recombinant protein (GST tag)
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Description
Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs) (PubMed:17110384). Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP (PubMed:26206488, PubMed:8702665). GNAS functions downstream of several GPCRs, including beta-adrenergic receptors (PubMed:21488135). Stimulates the Ras signaling pathway via RAPGEF2 (PubMed:12391161). {PubMed:12391161, PubMed:17110384, PubMed:21488135, PubMed:26206488, PubMed:8702665}.
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Protein name
Guanine nucleotide-binding protein G(s subunit alpha isoforms short
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Protein short names
GNAS1; GSP
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Uniprot ID
A0A7I2V5R6
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Gene Name
GNAS; GNAS1; GSP
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human GNAS (XP_016883301.1) 874-1038 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human NESP55,GNAS SDS-PAGE
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