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Product Name
Human NENF Recombinant protein (GST tag)
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Description
Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance (By similarity). Plays a role in the human tumorigenesis (PubMed:22748190). {UniProtKB:Q9CQ45, PubMed:22748190}.
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Protein name
Neudesin
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Protein short names
CIR2; SPUF
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Uniprot ID
Q9UMX5
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Gene Name
NENF; CIR2; SPUF
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the human NENF (NP_037481.1) 33-172 aa was fused with the N-terminal GST tag
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Protein Species
Human
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Activity
Not tested.
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Validations
Recombinant human NENF SDS-PAGE
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